8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_171154
Cell Name :  neuron-8_7
Archive Name :  Consiglio
Species Name :  human
Strain :  Not applicable
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Moderate
Morphological Attributes :  Diameter, 2D, Angles
Min Age :  68.0 years
Max Age :  68.0 years
Gender :  Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  Not reported
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  induced pluripotent stem cell-(iPSC)-derived
Tertiary Cell Class :  microtubule-associated protein 2 (MAP2) positive
Original Format :  Simple Neurite Tracer.traces
Experiment Protocol :  culture
Experimental Condition :  LRRK2 G2019S mutation
Staining Method :  immunostaining
Slicing Direction :  Not applicable
Slice Thickness :  Not applicable
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  63x
Reconstruction Method :  Simple Neurite Tracer
Date of Deposition :  2021-08-25
Date of Upload :  2021-12-21
Persistence Vector :  neuron-8_7.pvec
Note :  This reconstruction was obtained 80 days after differentiation.

Reference Article
Related Article Reference :  Parkinson's disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration.

Measurements
Soma Surface :  4.1 μm2
Number of Stems :  1
Number of Bifurcations :  1
Number of Branches :  3
Overall Width :  24.67 μm
Overall Height :  73.42 μm
Overall Depth :  0.07 μm
Average Diameter :  0.25 μm
Total Length :  124.22 μm
Total Surface :  97.6 μm2
Total Volume :  6.1 μm3
Max Euclidean Distance :  80.54 μm
Max Path Distance :  98.51 μm
Max Branch Order :  1
Average Contraction :  0.84
Total Fragmentation :  428
Partition Asymmetry :  0
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  2.58°
Average Bifurcation Angle Remote :  41.12°
Fractal Dimension :  1.05

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