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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_182108 |
| Cell Name : | neuron-5_10 |
| Archive Name : | Shcheglovitov |
| Species Name : | human |
| Strain : | Not applicable |
| Structural Domains : | Dendrites, Soma, No Axon |
| Physical Integrity : | Dendrites Moderate |
| Morphological Attributes : | No Diameter, 2D, Angles |
| Min Age : | Not reported
|
| Max Age : | Not reported
|
| Gender : |
Not reported
|
| Min Weight : | Not reported
|
| Max Weight : | Not reported
|
| Development : | not reported |
| Primary Brain Region : | neocortex |
| Secondary Brain Region : | Not reported |
| Tertiary Brain Region : | Not reported |
| Primary Cell Class : | principal cell |
| Secondary Cell Class : | embryonic stem cell (ESC)-derived |
| Tertiary Cell Class : | Not reported |
| Original Format : | Neurolucida.dat |
| Experiment Protocol : | in vivo |
| Experimental Condition : | hemizygous SHANK3 deletion |
| Staining Method : | biocytin |
| Slicing Direction : | coronal |
| Slice Thickness : | 300
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | oil |
| Magnification : | 20x |
| Reconstruction Method : | Neurolucida |
| Date of Deposition : | 2022-03-14 |
| Date of Upload : | 2022-04-14 |
| Persistence Vector : | neuron-5_10.pvec |
| Note : | Human ESC-derived neurons with cortical identity were transplanted in mouse PFC. This reconstruction was obtained at 13-17 months post-transplantation into the mouse PFC with SHANK3 +/-. |
|
|
| Reference Article |
| Related Article Reference : | Defective AMPA-mediated synaptic transmission and morphology in human neurons with hemizygous SHANK3 deletion engrafted in mouse prefrontal cortex. |
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| Measurements |
| Soma Surface : |
341.94 μm2 |
| Number of Stems : |
3 |
| Number of Bifurcations : |
16 |
| Number of Branches : |
35 |
| Overall Width : |
123.11 μm |
| Overall Height : |
220.38 μm |
| Overall Depth : |
0 μm |
| Average Diameter : |
0.98 μm |
| Total Length : |
1113.52 μm |
| Total Surface : |
3435.83 μm2 |
| Total Volume : |
967.42 μm3 |
| Max Euclidean Distance : |
138.16 μm |
| Max Path Distance : |
156.67 μm |
| Max Branch Order : |
6 |
| Average Contraction : |
0.85 |
| Total Fragmentation : |
1328 |
| Partition Asymmetry : |
0.5 |
| Average Rall's Ratio : |
1.48 |
| Average Bifurcation Angle Local : |
74.37° |
| Average Bifurcation Angle Remote : |
62.78° |
| Fractal Dimension : |
1.06 |
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