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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_182110 |
| Cell Name : | neuron-3_12 |
| Archive Name : | Shcheglovitov |
| Species Name : | human |
| Strain : | Not applicable |
| Structural Domains : | Dendrites, Soma, No Axon |
| Physical Integrity : | Dendrites Moderate |
| Morphological Attributes : | No Diameter, 3D, Angles |
| Min Age : | Not reported
|
| Max Age : | Not reported
|
| Gender : |
Not reported
|
| Min Weight : | Not reported
|
| Max Weight : | Not reported
|
| Development : | not reported |
| Primary Brain Region : | neocortex |
| Secondary Brain Region : | Not reported |
| Tertiary Brain Region : | Not reported |
| Primary Cell Class : | principal cell |
| Secondary Cell Class : | embryonic stem cell (ESC)-derived |
| Tertiary Cell Class : | Not reported |
| Original Format : | Neurolucida.dat |
| Experiment Protocol : | in vivo |
| Experimental Condition : | hemizygous SHANK3 deletion |
| Staining Method : | biocytin |
| Slicing Direction : | coronal |
| Slice Thickness : | 300
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | oil |
| Magnification : | 20x |
| Reconstruction Method : | Neurolucida |
| Date of Deposition : | 2022-03-14 |
| Date of Upload : | 2022-04-14 |
| Persistence Vector : | neuron-3_12.pvec |
| Note : | Human ESC-derived neurons with cortical identity were transplanted in mouse PFC. This reconstruction was obtained at 13-17 months post-transplantation into the mouse PFC with SHANK3 +/-. |
|
|
| Reference Article |
| Related Article Reference : | Defective AMPA-mediated synaptic transmission and morphology in human neurons with hemizygous SHANK3 deletion engrafted in mouse prefrontal cortex. |
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| Measurements |
| Soma Surface : |
454.27 μm2 |
| Number of Stems : |
3 |
| Number of Bifurcations : |
17 |
| Number of Branches : |
37 |
| Overall Width : |
191.89 μm |
| Overall Height : |
515.96 μm |
| Overall Depth : |
19.69 μm |
| Average Diameter : |
1.32 μm |
| Total Length : |
1791.55 μm |
| Total Surface : |
7609.75 μm2 |
| Total Volume : |
3163.44 μm3 |
| Max Euclidean Distance : |
344.22 μm |
| Max Path Distance : |
505.34 μm |
| Max Branch Order : |
8 |
| Average Contraction : |
0.82 |
| Total Fragmentation : |
1436 |
| Partition Asymmetry : |
0.73 |
| Average Rall's Ratio : |
2.22 |
| Average Bifurcation Angle Local : |
80.22° |
| Average Bifurcation Angle Remote : |
71.29° |
| Fractal Dimension : |
1.05 |
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