8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_182104
Cell Name :  neuron-2_10
Archive Name :  Shcheglovitov
Species Name :  human
Strain :  Not applicable
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Moderate
Morphological Attributes :  No Diameter, 2D, Angles
Min Age :  Not reported
Max Age :  Not reported
Gender :  Not reported
Min Weight :  Not reported
Max Weight :  Not reported
Development :  not reported
Primary Brain Region :  neocortex
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  embryonic stem cell (ESC)-derived
Tertiary Cell Class :  Not reported
Original Format :  Neurolucida.dat
Experiment Protocol :  in vivo
Experimental Condition :  Control
Staining Method :  biocytin
Slicing Direction :  coronal
Slice Thickness :  300  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  20x
Reconstruction Method :  Neurolucida
Date of Deposition :  2022-03-14
Date of Upload :  2022-04-14
Persistence Vector :  neuron-2_10.pvec
Note :  Human ESC-derived neurons with cortical identity were transplanted in mouse PFC. This reconstruction was obtained at 13-17 months post-transplantation into the mouse PFC with the isogenic control (iCtrl).

Reference Article
Related Article Reference :  Defective AMPA-mediated synaptic transmission and morphology in human neurons with hemizygous SHANK3 deletion engrafted in mouse prefrontal cortex.

Measurements
Soma Surface :  8688.42 μm2
Number of Stems :  3
Number of Bifurcations :  6
Number of Branches :  15
Overall Width :  331.76 μm
Overall Height :  1755.06 μm
Overall Depth :  0 μm
Average Diameter :  9.07 μm
Total Length :  3685.14 μm
Total Surface :  98953.5 μm2
Total Volume :  242719 μm3
Max Euclidean Distance :  1254.47 μm
Max Path Distance :  1540.28 μm
Max Branch Order :  3
Average Contraction :  0.9
Total Fragmentation :  493
Partition Asymmetry :  0.39
Average Rall's Ratio :  1.67
Average Bifurcation Angle Local :  45.06°
Average Bifurcation Angle Remote :  101.42°
Fractal Dimension :  1.02

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