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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_157256 |
| Cell Name : | dysk-3 |
| Archive Name : | Murer |
| Species Name : | mouse |
| Strain : | ChaT-IRES-Cre:Ai14 |
| Structural Domains : | Dendrites, Soma, No Axon |
| Physical Integrity : | Dendrites Moderate |
| Morphological Attributes : | No Diameter, 3D, Angles |
| Min Age : | 90.0 days
|
| Max Age : | 150.0 days
|
| Gender : |
Female
|
| Min Weight : | 20 grams
|
| Max Weight : | 30 grams
|
| Development : | adult |
| Primary Brain Region : | basal ganglia |
| Secondary Brain Region : | striatum |
| Tertiary Brain Region : | dorsolateral |
| Primary Cell Class : | interneuron |
| Secondary Cell Class : | cholinergic |
| Tertiary Cell Class : | Not reported |
| Original Format : | Neurolucida.dat |
| Experiment Protocol : | ex vivo |
| Experimental Condition : | 6-hydroxydopamine (6-OHDA)-lesion + L-DOPA treatment |
| Staining Method : | Neurobiotin, Streptavidin-Alexa 488 |
| Slicing Direction : | coronal |
| Slice Thickness : | 300
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | dry |
| Magnification : | 20x |
| Reconstruction Method : | Neurolucida |
| Date of Deposition : | 2021-06-03 |
| Date of Upload : | 2021-06-21 |
| Persistence Vector : | dysk-3.pvec |
| Note : | The diameter of the dendrite reconstructions may not be accurate, so the corresponding measures in the measurements table should not be used for quantitative analysis or modeling. This group corresponds to mice rendered severely parkinsonian (unilateral injection of 6-OHDA in the MFB, >85% dopaminergic lesion) and treated during 14 days with 12mg/kg L-DOPA/benserazide that induced severe dyskinesias. Slices were obtained 24h after the last injection of L-DOPA/benserazide. |
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| Reference Article |
| Related Article Reference : | Levodopa Causes Striatal Cholinergic Interneuron Burst-Pause Activity in Parkinsonian Mice. |
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| Measurements |
| Soma Surface : |
523.62 μm2 |
| Number of Stems : |
3 |
| Number of Bifurcations : |
17 |
| Number of Branches : |
37 |
| Overall Width : |
279.88 μm |
| Overall Height : |
320.62 μm |
| Overall Depth : |
86.55 μm |
| Average Diameter : |
1.3 μm |
| Total Length : |
2827.81 μm |
| Total Surface : |
11785.7 μm2 |
| Total Volume : |
4337.72 μm3 |
| Max Euclidean Distance : |
301.94 μm |
| Max Path Distance : |
415.4 μm |
| Max Branch Order : |
6 |
| Average Contraction : |
0.8 |
| Total Fragmentation : |
1355 |
| Partition Asymmetry : |
0.46 |
| Average Rall's Ratio : |
2.65 |
| Average Bifurcation Angle Local : |
64.37° |
| Average Bifurcation Angle Remote : |
64.28° |
| Fractal Dimension : |
1.06 |
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