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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_253096 |
| Cell Name : | cell_3xtg_ucp_5 |
| Archive Name : | Rosenberg |
| Species Name : | mouse |
| Strain : | 3 x Tg-AD |
| Structural Domains : | Dendrites, Soma, No Axon |
| Physical Integrity : | Dendrites Moderate |
| Morphological Attributes : | No Diameter, 3D, Angles |
| Min Age : | 7.0 months
|
| Max Age : | 10.0 months
|
| Gender : |
Male
|
| Min Weight : | Not reported
|
| Max Weight : | Not reported
|
| Development : | adult |
| Primary Brain Region : | subiculum |
| Secondary Brain Region : | Not reported |
| Tertiary Brain Region : | Not reported |
| Primary Cell Class : | principal cell |
| Secondary Cell Class : | pyramidal |
| Tertiary Cell Class : | Not reported |
| Original Format : | Imaris.swc |
| Experiment Protocol : | in vitro |
| Experimental Condition : | uncoupling protein 4 (UCP4) overexpression |
| Staining Method : | biocytin |
| Slicing Direction : | Sagittal |
| Slice Thickness : | 300
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | dry |
| Magnification : | 20x |
| Reconstruction Method : | Imaris |
| Date of Deposition : | 2023-01-18 |
| Date of Upload : | 2023-02-07 |
| Persistence Vector : | cell_3xtg_ucp_5.pvec |
| Note : | 3xTg-AD mice were injected bilaterally in two sites in the hippocampus (site 1. Antero-posterior: -1 mm, mediolateral: +/-1.46 mm, ventral: -1.5 from bregma; site 2. Antero-posterior: -1.56 mm, mediolateral: +/-2.15 mm, ventral: -1.5 from bregma) with a virus encoding AAV9-mCherry-UCP4. 3 microliters were injected at a rate of 100-200 nl/min at each injection site. |
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| Reference Article |
| Related Article Reference : | Overexpression of UCP4 in astrocytic mitochondria prevents multilevel dysfunctions in a mouse model of Alzheimer''s disease. |
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| Measurements |
| Soma Surface : |
1121.02 μm2 |
| Number of Stems : |
5 |
| Number of Bifurcations : |
64 |
| Number of Branches : |
133 |
| Overall Width : |
233.77 μm |
| Overall Height : |
503.49 μm |
| Overall Depth : |
43.32 μm |
| Average Diameter : |
1.93 μm |
| Total Length : |
4769.29 μm |
| Total Surface : |
28806.5 μm2 |
| Total Volume : |
14140.2 μm3 |
| Max Euclidean Distance : |
413.04 μm |
| Max Path Distance : |
524.84 μm |
| Max Branch Order : |
23 |
| Average Contraction : |
0.93 |
| Total Fragmentation : |
4372 |
| Partition Asymmetry : |
0.59 |
| Average Rall's Ratio : |
1.99 |
| Average Bifurcation Angle Local : |
9.72° |
| Average Bifurcation Angle Remote : |
61.54° |
| Fractal Dimension : |
1.02 |
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