8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_253104
Cell Name :  cell_3xgt_ucp_3
Archive Name :  Rosenberg
Species Name :  mouse
Strain :  3 x Tg-AD
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Moderate
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  7.0 months
Max Age :  10.0 months
Gender :  Male
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  subiculum
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  pyramidal
Tertiary Cell Class :  Not reported
Original Format :  Imaris.swc
Experiment Protocol :  in vitro
Experimental Condition :  uncoupling protein 4 (UCP4) overexpression
Staining Method :  biocytin
Slicing Direction :  Sagittal
Slice Thickness :  300  μm
Tissue Shrinkage :  Not reported
Objective Type :  dry
Magnification :  20x
Reconstruction Method :  Imaris
Date of Deposition :  2023-01-18
Date of Upload :  2023-02-07
Persistence Vector :  cell_3xgt_ucp_3.pvec
Note :  3xTg-AD mice were injected bilaterally in two sites in the hippocampus (site 1. Antero-posterior: -1 mm, mediolateral: +/-1.46 mm, ventral: -1.5 from bregma; site 2. Antero-posterior: -1.56 mm, mediolateral: +/-2.15 mm, ventral: -1.5 from bregma) with a virus encoding AAV9-mCherry-UCP4. 3 microliters were injected at a rate of 100-200 nl/min at each injection site.

Reference Article
Related Article Reference :  Overexpression of UCP4 in astrocytic mitochondria prevents multilevel dysfunctions in a mouse model of Alzheimer''s disease.

Measurements
Soma Surface :  966.74 μm2
Number of Stems :  3
Number of Bifurcations :  93
Number of Branches :  189
Overall Width :  183.64 μm
Overall Height :  580.28 μm
Overall Depth :  18.54 μm
Average Diameter :  1.87 μm
Total Length :  5630.45 μm
Total Surface :  33119.3 μm2
Total Volume :  15503.3 μm3
Max Euclidean Distance :  431.29 μm
Max Path Distance :  652.79 μm
Max Branch Order :  29
Average Contraction :  0.95
Total Fragmentation :  6003
Partition Asymmetry :  0.58
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  17.04°
Average Bifurcation Angle Remote :  59.66°
Fractal Dimension :  1.01

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