8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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Details about selected cell
NeuroMorpho.Org ID :  NMO_274290
Cell Name :  batch3_DRAV_div49_6-1
Archive Name :  Doorn
Species Name :  human
Strain :  Not applicable
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Complete
Morphological Attributes :  No Diameter, 2D, Angles
Min Age :  4.0 years
Max Age :  4.0 years
Gender :  Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  infant
Primary Brain Region :  Not reported
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  induced pluripotent stem cell-(iPSC)-derived
Tertiary Cell Class :  Neurogenin-2 (NGN2) induced
Original Format :  Neurolucida.dat
Experiment Protocol :  culture
Experimental Condition :  SCN1A missense mutation
Staining Method :  immunostaining
Slicing Direction :  Not applicable
Slice Thickness :  Not applicable
Tissue Shrinkage :  Not reported
Objective Type :  dry
Magnification :  20x
Reconstruction Method :  Neurolucida
Date of Deposition :  2023-09-25
Date of Upload :  2023-10-16
Persistence Vector :  batch3_DRAV_div49_6-1.pvec
Note :  This reconstruction was obtained after 49 days in vitro.

Reference Article
Related Article Reference :  An in silico and in vitro human neuronal network model reveals cellular mechanisms beyond NaV1.1 underlying Dravet syndrome.

Measurements
Soma Surface :  1137.5 μm2
Number of Stems :  8
Number of Bifurcations :  11
Number of Branches :  30
Overall Width :  244.38 μm
Overall Height :  301.3 μm
Overall Depth :  0.01 μm
Average Diameter :  0.74 μm
Total Length :  1550.34 μm
Total Surface :  2853.97 μm2
Total Volume :  851.61 μm3
Max Euclidean Distance :  200.49 μm
Max Path Distance :  204.68 μm
Max Branch Order :  3
Average Contraction :  0.98
Total Fragmentation :  133
Partition Asymmetry :  0.18
Average Rall's Ratio :  0.95
Average Bifurcation Angle Local :  45.05°
Average Bifurcation Angle Remote :  46.39°
Fractal Dimension :  1

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