8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_139475
Cell Name :  Q97-D2-Jun20IR2d
Archive Name :  Luebke
Species Name :  mouse
Strain :  Drd2-eGFP x BACHDdeltaN17 (Q97)
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Moderate
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  9.0 months
Max Age :  9.0 months
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  basal ganglia
Secondary Brain Region :  striatum
Tertiary Brain Region :  dorsolateral
Primary Cell Class :  principal cell
Secondary Cell Class :  medium spiny
Tertiary Cell Class :  D2-type dopamine receptor-expressing
Original Format :  Neuronstudio.swc
Experiment Protocol :  in vitro
Experimental Condition :  deletion of the N17 domain of the Huntingtin gene
Staining Method :  Biocytin, Streptavidin-Alexa 405
Slicing Direction :  coronal
Slice Thickness :  300  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  40x
Reconstruction Method :  NeuronStudio
Date of Deposition :  2020-08-08
Date of Upload :  2020-09-15
Persistence Vector :  Q97-D2-Jun20IR2d.pvec
Note :  97 CAG repeats. D2 (eGFP+) MSNs in the dorsolateral striatum were provisionally identified at the time of recordings by visualizing MSN somata under infrared-differential interference contrast (IR-DIC) optics then switching to epifluorescence optics to determine if the somata showed GFP signal.

Reference Article
Related Article Reference :  Structural and functional features of medium spiny neurons in the BACHDΔN17 mouse model of Huntington's Disease.

Measurements
Soma Surface :  37.92 μm2
Number of Stems :  2
Number of Bifurcations :  12
Number of Branches :  26
Overall Width :  41.72 μm
Overall Height :  92.79 μm
Overall Depth :  9.39 μm
Average Diameter :  0.5 μm
Total Length :  478.93 μm
Total Surface :  749.88 μm2
Total Volume :  102.28 μm3
Max Euclidean Distance :  56.81 μm
Max Path Distance :  59.97 μm
Max Branch Order :  5
Average Contraction :  0.93
Total Fragmentation :  553
Partition Asymmetry :  0.4
Average Rall's Ratio :  1.75
Average Bifurcation Angle Local :  68.46°
Average Bifurcation Angle Remote :  31.09°
Fractal Dimension :  1.03

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