8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_139481
Cell Name :  Q31-D2-Aug28IR3b
Archive Name :  Luebke
Species Name :  mouse
Strain :  Drd2-eGFP x BACWTdeltaN17 (Q31)
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Moderate
Morphological Attributes :  Diameter, 3D, Angles
Min Age :  9.0 months
Max Age :  9.0 months
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  basal ganglia
Secondary Brain Region :  striatum
Tertiary Brain Region :  dorsolateral
Primary Cell Class :  principal cell
Secondary Cell Class :  medium spiny
Tertiary Cell Class :  D2-type dopamine receptor-expressing
Original Format :  Neuronstudio.swc
Experiment Protocol :  in vitro
Experimental Condition :  deletion of the N17 domain of the Huntingtin gene
Staining Method :  Biocytin, Streptavidin-Alexa 405
Slicing Direction :  coronal
Slice Thickness :  300  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  40x
Reconstruction Method :  NeuronStudio
Date of Deposition :  2020-08-08
Date of Upload :  2020-09-15
Persistence Vector :  Q31-D2-Aug28IR3b.pvec
Note :  31 CAG repeats. D2 (eGFP+) MSNs in the dorsolateral striatum were provisionally identified at the time of recordings by visualizing MSN somata under infrared-differential interference contrast (IR-DIC) optics then switching to epifluorescence optics to determine if the somata showed GFP signal.

Reference Article
Related Article Reference :  Structural and functional features of medium spiny neurons in the BACHDΔN17 mouse model of Huntington's Disease.

Measurements
Soma Surface :  363.35 μm2
Number of Stems :  8
Number of Bifurcations :  24
Number of Branches :  56
Overall Width :  149.65 μm
Overall Height :  245.24 μm
Overall Depth :  40.77 μm
Average Diameter :  1.51 μm
Total Length :  2610.78 μm
Total Surface :  13576.3 μm2
Total Volume :  6509.41 μm3
Max Euclidean Distance :  164.5 μm
Max Path Distance :  181.23 μm
Max Branch Order :  5
Average Contraction :  0.89
Total Fragmentation :  2193
Partition Asymmetry :  0.29
Average Rall's Ratio :  1.09
Average Bifurcation Angle Local :  77.72°
Average Bifurcation Angle Remote :  78.47°
Fractal Dimension :  1.03

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