8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
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Log File (Original)



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NeuroMorpho.Org ID :  NMO_139469
Cell Name :  Q31-D1-Aug2IR3b-whole-cell
Archive Name :  Luebke
Species Name :  mouse
Strain :  Drd2-eGFP x BACWTdeltaN17 (Q31)
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Moderate
Morphological Attributes :  Diameter, 3D, Angles
Min Age :  9.0 months
Max Age :  9.0 months
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  basal ganglia
Secondary Brain Region :  striatum
Tertiary Brain Region :  dorsolateral
Primary Cell Class :  principal cell
Secondary Cell Class :  medium spiny
Tertiary Cell Class :  D1-type dopamine receptor-expressing
Original Format :  Neuronstudio.swc
Experiment Protocol :  in vitro
Experimental Condition :  deletion of the N17 domain of the Huntingtin gene
Staining Method :  Biocytin, Streptavidin-Alexa 405
Slicing Direction :  coronal
Slice Thickness :  300  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  40x
Reconstruction Method :  NeuronStudio
Date of Deposition :  2020-08-08
Date of Upload :  2020-09-15
Persistence Vector :  Q31-D1-Aug2IR3b-whole-cell.pvec
Note :  31 CAG repeats. D1 (eGFP-) MSNs in the dorsolateral striatum were provisionally identified at the time of recordings by visualizing MSN somata under infrared-differential interference contrast (IR-DIC) optics then switching to epifluorescence optics to determine if the somata showed GFP signal.

Reference Article
Related Article Reference :  Structural and functional features of medium spiny neurons in the BACHDΔN17 mouse model of Huntington's Disease.

Measurements
Soma Surface :  380.18 μm2
Number of Stems :  3
Number of Bifurcations :  14
Number of Branches :  31
Overall Width :  184 μm
Overall Height :  262.38 μm
Overall Depth :  36.5 μm
Average Diameter :  1.71 μm
Total Length :  1867.38 μm
Total Surface :  10315 μm2
Total Volume :  5244.63 μm3
Max Euclidean Distance :  179 μm
Max Path Distance :  207.98 μm
Max Branch Order :  4
Average Contraction :  0.86
Total Fragmentation :  675
Partition Asymmetry :  0.3
Average Rall's Ratio :  1.85
Average Bifurcation Angle Local :  67.19°
Average Bifurcation Angle Remote :  60.53°
Fractal Dimension :  1.06

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