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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_302879 |
| Cell Name : | NG14-3PIO_4DIV-NPC2-GFP-PDE-filipin-LAMP-1b |
| Archive Name : | Soto |
| Species Name : | mouse |
| Strain : | Npc1nmf164-Pcp2EGF;B6;FVB-Tg(Pcp2-EGFP)2Yuza/J |
| Structural Domains : | Dendrites, Soma, No Axon |
| Physical Integrity : | Dendrites Moderate |
| Morphological Attributes : | Diameter, 3D, Angles |
| Min Age : | 10.0 days
|
| Max Age : | 10.0 days
|
| Gender : |
Male/Female
|
| Min Weight : | Not reported
|
| Max Weight : | Not reported
|
| Development : | young |
| Primary Brain Region : | cerebellum |
| Secondary Brain Region : | Not reported |
| Tertiary Brain Region : | Not reported |
| Primary Cell Class : | principal cell |
| Secondary Cell Class : | Purkinje |
| Tertiary Cell Class : | LAMP1-positive, pyruvate dehydrogenase-E1 alpha (PDE)-positive, Filipin-positive, NPC2 |
| Original Format : | Imaris.ims |
| Experiment Protocol : | in vitro |
| Experimental Condition : | NPC1 mutant |
| Staining Method : | immunostaining |
| Slicing Direction : | Not reported |
| Slice Thickness : | 250
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | water |
| Magnification : | 40x |
| Reconstruction Method : | Imaris |
| Date of Deposition : | 2024-05-14 |
| Date of Upload : | 2025-09-25 |
| Persistence Vector : | NG14-3PIO_4DIV-NPC2-GFP-PDE-filipin-LAMP-1b.pvec |
|
|
| Reference Article |
| Related Article Reference : | Trehalose enhances mitochondria deficits in human NPC1 mutant fibroblasts but disrupts mouse Purkinje cell dendritic growth ex vivo. |
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|
| Measurements |
| Soma Surface : |
579.19 μm2 |
| Number of Stems : |
3 |
| Number of Bifurcations : |
66 |
| Number of Branches : |
135 |
| Overall Width : |
48.88 μm |
| Overall Height : |
129.8 μm |
| Overall Depth : |
3.99 μm |
| Average Diameter : |
1.89 μm |
| Total Length : |
897.77 μm |
| Total Surface : |
5315.36 μm2 |
| Total Volume : |
3221.82 μm3 |
| Max Euclidean Distance : |
130.47 μm |
| Max Path Distance : |
145.82 μm |
| Max Branch Order : |
29 |
| Average Contraction : |
0.92 |
| Total Fragmentation : |
3059 |
| Partition Asymmetry : |
0.72 |
| Average Rall's Ratio : |
1.99 |
| Average Bifurcation Angle Local : |
32.33° |
| Average Bifurcation Angle Remote : |
47.22° |
| Fractal Dimension : |
1.04 |
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