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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_283921 |
| Cell Name : | Ms245_40HzFlicker_1h_IBA1_pJNKpERKInh_02 |
| Archive Name : | Prichard_Singer |
| Species Name : | mouse |
| Strain : | C57BL/6J |
| Structural Domains : | Processes, Soma |
| Physical Integrity : | Processes Complete |
| Morphological Attributes : | Diameter, 3D, Angles |
| Min Age : | 2.0 months
|
| Max Age : | 2.0 months
|
| Gender : |
Male
|
| Min Weight : | 30 grams
|
| Max Weight : | 30 grams
|
| Development : | adult |
| Primary Brain Region : | neocortex |
| Secondary Brain Region : | occipital |
| Tertiary Brain Region : | primary visual, right |
| Primary Cell Class : | Glia |
| Secondary Cell Class : | microglia |
| Tertiary Cell Class : | Iba1-positive |
| Original Format : | Imaris.ims |
| Experiment Protocol : | in vitro |
| Experimental Condition : | MAPK inhibitor + visual flicker |
| Staining Method : | immunostaining |
| Slicing Direction : | Sagittal |
| Slice Thickness : | 40
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | oil |
| Magnification : | 20x , 40x |
| Reconstruction Method : | Imaris |
| Date of Deposition : | 2023-07-28 |
| Date of Upload : | 2024-07-30 |
| Persistence Vector : | Ms245_40HzFlicker_1h_IBA1_pJNKpERKInh_02.pvec |
| Note : | Mice were injected intraperitoneally with MAPK [MAPK/MAPK kinase (MEK) inhibitor SL327 (100 mg/kg) plus MAPK/c-Jun N-terminal kinase (JNK) inhibitor SP600125 (15 mg/kg)] pathways 1 hour before exposing animals to flicker. Animals were exposed to LED lights flashing at 40 Hz frequency (50% duty cycle: 12.5-ms light on and 12.5-ms light off) for 1 hour. |
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| Reference Article |
| Related Article Reference : | Brain rhythms control microglial response and cytokine expression via NF-κB signaling. |
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| Measurements |
| Soma Surface : |
950.46 μm2 |
| Number of Stems : |
21 |
| Number of Bifurcations : |
34 |
| Number of Branches : |
89 |
| Overall Width : |
12.96 μm |
| Overall Height : |
36.74 μm |
| Overall Depth : |
26.3 μm |
| Average Diameter : |
1.05 μm |
| Total Length : |
361.19 μm |
| Total Surface : |
1199.09 μm2 |
| Total Volume : |
402.71 μm3 |
| Max Euclidean Distance : |
24.69 μm |
| Max Path Distance : |
43.78 μm |
| Max Branch Order : |
14 |
| Average Contraction : |
0.87 |
| Total Fragmentation : |
1580 |
| Partition Asymmetry : |
0.62 |
| Average Rall's Ratio : |
2.02 |
| Average Bifurcation Angle Local : |
62.52° |
| Average Bifurcation Angle Remote : |
71.92° |
| Fractal Dimension : |
1.07 |
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