8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_284872
Cell Name :  Ms241_40HzFlicker_1h_IBA1_pJNKpERKInh_21
Archive Name :  Prichard_Singer
Species Name :  mouse
Strain :  C57BL/6J
Structural Domains :  Processes, Soma
Physical Integrity :  Processes Complete
Morphological Attributes :  Diameter, 3D, Angles
Min Age :  2.0 months
Max Age :  2.0 months
Gender :  Male
Min Weight :  30 grams
Max Weight :  30 grams
Development :  adult
Primary Brain Region :  neocortex
Secondary Brain Region :  occipital
Tertiary Brain Region :  primary visual, right
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Iba1-positive
Original Format :  Imaris.ims
Experiment Protocol :  in vitro
Experimental Condition :  MAPK inhibitor + visual flicker
Staining Method :  immunostaining
Slicing Direction :  Sagittal
Slice Thickness :  40  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  20x , 40x
Reconstruction Method :  Imaris
Date of Deposition :  2023-07-28
Date of Upload :  2024-07-30
Persistence Vector :  Ms241_40HzFlicker_1h_IBA1_pJNKpERKInh_21.pvec
Note :  Mice were injected intraperitoneally with MAPK [MAPK/MAPK kinase (MEK) inhibitor SL327 (100 mg/kg) plus MAPK/c-Jun N-terminal kinase (JNK) inhibitor SP600125 (15 mg/kg)] pathways 1 hour before exposing animals to flicker. Animals were exposed to LED lights flashing at 40 Hz frequency (50% duty cycle: 12.5-ms light on and 12.5-ms light off) for 1 hour.

Reference Article
Related Article Reference :  Brain rhythms control microglial response and cytokine expression via NF-κB signaling.

Measurements
Soma Surface :  631.11 μm2
Number of Stems :  11
Number of Bifurcations :  31
Number of Branches :  73
Overall Width :  13.73 μm
Overall Height :  65.78 μm
Overall Depth :  36.1 μm
Average Diameter :  1.41 μm
Total Length :  383.83 μm
Total Surface :  1745.14 μm2
Total Volume :  724.58 μm3
Max Euclidean Distance :  39.55 μm
Max Path Distance :  57.9 μm
Max Branch Order :  10
Average Contraction :  0.87
Total Fragmentation :  1812
Partition Asymmetry :  0.63
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  55.02°
Average Bifurcation Angle Remote :  68.19°
Fractal Dimension :  1.06

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