8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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Details about selected cell
NeuroMorpho.Org ID :  NMO_171326
Cell Name :  MC3-SP13D50n2_TH-Fox-Girk_63x-S6_b
Archive Name :  Consiglio
Species Name :  human
Strain :  Not applicable
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Moderate
Morphological Attributes :  No Diameter, 2D, Angles
Min Age :  68.0 years
Max Age :  68.0 years
Gender :  Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  Not reported
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  induced pluripotent stem cell-(iPSC)-derived
Tertiary Cell Class :  tyrosine hydroxylase (TH) positive
Original Format :  NeuronJ.ndf
Experiment Protocol :  culture
Experimental Condition :  LRRK2 G2019S mutation
Staining Method :  immunostaining
Slicing Direction :  Not applicable
Slice Thickness :  Not applicable
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  63x
Reconstruction Method :  NeuronJ
Date of Deposition :  2021-08-25
Date of Upload :  2021-12-21
Persistence Vector :  MC3-SP13D50n2_TH-Fox-Girk_63x-S6_b.pvec
Note :  This reconstruction was obtained 50 days after differentiation.

Reference Article
Related Article Reference :  Parkinson's disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration.

Measurements
Soma Surface :  4315.12 μm2
Number of Stems :  3
Number of Bifurcations :  4
Number of Branches :  11
Overall Width :  99.23 μm
Overall Height :  206.88 μm
Overall Depth :  0 μm
Average Diameter :  1 μm
Total Length :  598.16 μm
Total Surface :  1879.19 μm2
Total Volume :  469.8 μm3
Max Euclidean Distance :  139.14 μm
Max Path Distance :  149.93 μm
Max Branch Order :  2
Average Contraction :  0.95
Total Fragmentation :  104
Partition Asymmetry :  0.5
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  94.95°
Average Bifurcation Angle Remote :  59.87°
Fractal Dimension :  1.01

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