8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_173125
Cell Name :  MAX_30-KOTTR-GFp-CtA3_1-1_1
Archive Name :  Gomes
Species Name :  mouse
Strain :  TTR -/-
Structural Domains :  Neurites, Soma
Physical Integrity :  Neurites Complete
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  16.0 days
Max Age :  16.0 days
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  embryonic
Primary Brain Region :  hippocampus
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  Not reported
Tertiary Cell Class :  Not reported
Original Format :  NeuronJ.ndf
Experiment Protocol :  culture
Experimental Condition :  megalin overexpression
Staining Method :  green fluorescent protein
Slicing Direction :  Not applicable
Slice Thickness :  Not applicable
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  40x
Reconstruction Method :  NeuronJ
Date of Deposition :  2021-10-07
Date of Upload :  2022-01-12
Persistence Vector :  MAX_30-KOTTR-GFp-CtA3_1-1_1.pvec
Note :  TTR KO cultured hippocampal neurons (11 DIV) were co-transfected with GFP (pEGFP) and mini-megalin plasmid (pLNCX-M4) for 48 h, and not stimulated for 24 h.

Reference Article
Related Article Reference :  Neuronal megalin mediates synaptic plasticity-a novel mechanism underlying intellectual disabilities in megalin gene pathologies.

Measurements
Soma Surface :  11847.7 μm2
Number of Stems :  13
Number of Bifurcations :  6
Number of Branches :  25
Overall Width :  751.52 μm
Overall Height :  395.58 μm
Overall Depth :  4.46 μm
Average Diameter :  1 μm
Total Length :  3520.54 μm
Total Surface :  11060.1 μm2
Total Volume :  2765.03 μm3
Max Euclidean Distance :  472.48 μm
Max Path Distance :  491.5 μm
Max Branch Order :  2
Average Contraction :  0.96
Total Fragmentation :  580
Partition Asymmetry :  0.33
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  29.32°
Average Bifurcation Angle Remote :  43.44°
Fractal Dimension :  1.01

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