8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



3D Cell Viewer - Java, legacy
3D Cell Viewer - WebGL, novel
Animation
Similar Neurons
Details about selected cell
NeuroMorpho.Org ID :  NMO_173076
Cell Name :  MAX_30-KOTTR-GFP_2-MsTTR55_A2_3
Archive Name :  Gomes
Species Name :  mouse
Strain :  TTR -/-
Structural Domains :  Neurites, Soma
Physical Integrity :  Neurites Complete
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  16.0 days
Max Age :  16.0 days
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  embryonic
Primary Brain Region :  hippocampus
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  Not reported
Tertiary Cell Class :  Not reported
Original Format :  NeuronJ.ndf
Experiment Protocol :  culture
Experimental Condition :  transthyretin (TTR) stimulation
Staining Method :  green fluorescent protein
Slicing Direction :  Not applicable
Slice Thickness :  Not applicable
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  40x
Reconstruction Method :  NeuronJ
Date of Deposition :  2021-10-07
Date of Upload :  2022-01-12
Persistence Vector :  MAX_30-KOTTR-GFP_2-MsTTR55_A2_3.pvec
Note :  TTR KO cultured hippocampal neurons (11 DIV) were transfected GFP plasmid (pEGFP) for 48 h, and stimulated, with recombinant mouse TTR (55 mg/ml) for 24 h.

Reference Article
Related Article Reference :  Neuronal megalin mediates synaptic plasticity-a novel mechanism underlying intellectual disabilities in megalin gene pathologies.

Measurements
Soma Surface :  8937.44 μm2
Number of Stems :  10
Number of Bifurcations :  14
Number of Branches :  38
Overall Width :  636.82 μm
Overall Height :  527.95 μm
Overall Depth :  5.33 μm
Average Diameter :  1.04 μm
Total Length :  3430.84 μm
Total Surface :  12324.2 μm2
Total Volume :  13585.6 μm3
Max Euclidean Distance :  642.74 μm
Max Path Distance :  800.3 μm
Max Branch Order :  6
Average Contraction :  0.96
Total Fragmentation :  591
Partition Asymmetry :  0.71
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  62.89°
Average Bifurcation Angle Remote :  60.78°
Fractal Dimension :  1.01

© Copyright 2006-2025   George Mason University All Rights Reserved.   Link Graphic to NIF website