8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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Details about selected cell
NeuroMorpho.Org ID :  NMO_166453
Cell Name :  M146V
Archive Name :  Ghatak_Lipton
Species Name :  human
Strain :  Not applicable
Structural Domains :  Neurites, No Soma
Physical Integrity :  Neurites Complete
Morphological Attributes :  No Diameter, 2D, Angles
Min Age :  Not reported
Max Age :  Not reported
Gender :  Not reported
Min Weight :  Not reported
Max Weight :  Not reported
Development :  not reported
Primary Brain Region :  neocortex
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  induced pluripotent stem cell-(iPSC)-derived
Tertiary Cell Class :  Not reported
Original Format :  Simple Neurite Tracer.traces
Experiment Protocol :  in vitro
Experimental Condition :  PS1 M146V mutant
Staining Method :  Golgi
Slicing Direction :  Not reported
Slice Thickness :  200  μm
Tissue Shrinkage :  Not reported
Objective Type :  dry
Magnification :  20x
Reconstruction Method :  Simple Neurite Tracer
Date of Deposition :  2021-09-27
Date of Upload :  2021-10-26
Persistence Vector :  M146V.pvec

Reference Article
Related Article Reference :  Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls.

Measurements
Soma Surface :  N/A
Number of Stems :  1
Number of Bifurcations :  12
Number of Branches :  25
Overall Width :  974.57 μm
Overall Height :  307.23 μm
Overall Depth :  0 μm
Average Diameter :  0.25 μm
Total Length :  1923.33 μm
Total Surface :  1510.58 μm2
Total Volume :  94.41 μm3
Max Euclidean Distance :  1017.6 μm
Max Path Distance :  1335.64 μm
Max Branch Order :  8
Average Contraction :  0.93
Total Fragmentation :  1337
Partition Asymmetry :  0.52
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  63.81°
Average Bifurcation Angle Remote :  69.72°
Fractal Dimension :  1.02

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