8.6.69 - Released: 2025-01-27 - Content: 272520 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_295463
Cell Name :  LPS_microglia_Veh_4_Section_1_cel_1
Archive Name :  Kodali_Shetty
Species Name :  mouse
Strain :  C57BL/6J
Structural Domains :  Processes, Soma
Physical Integrity :  Processes Moderate
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  70.0 days
Max Age :  70.0 days
Gender :  Male
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  hippocampus
Secondary Brain Region :  CA3
Tertiary Brain Region :  stratum radiatum
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Iba1-positive
Original Format :  Neurolucida.dat
Experiment Protocol :  in vitro
Experimental Condition :  lipopolysaccharide injection
Staining Method :  immunostaining
Slicing Direction :  coronal
Slice Thickness :  30  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  100x
Reconstruction Method :  Neurolucida
Date of Deposition :  2024-09-09
Date of Upload :  2025-01-27
Persistence Vector :  LPS_microglia_Veh_4_Section_1_cel_1.pvec
Note :  This reconstruction was obtained from a mouse that received daily intraperitoneal injections of LPS (Escherichia coli serotype: 0111:B4; Sigma-Aldrich, St. Louis, MO, USA) dissolved in normal saline at a dose of 0.75 mg/kg for seven consecutive days (days 1-7). Starting from day 8, the mouse received three IN doses of PBS over 6 days, with each dose separated by two days.

Reference Article
Related Article Reference :  Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis in the hippocampus.

Measurements
Soma Surface :  42683.2 μm2
Number of Stems :  3
Number of Bifurcations :  40
Number of Branches :  83
Overall Width :  588.11 μm
Overall Height :  398.92 μm
Overall Depth :  4.36 μm
Average Diameter :  0.86 μm
Total Length :  4475.34 μm
Total Surface :  12091.3 μm2
Total Volume :  2599.64 μm3
Max Euclidean Distance :  388.48 μm
Max Path Distance :  676.26 μm
Max Branch Order :  11
Average Contraction :  0.89
Total Fragmentation :  537
Partition Asymmetry :  0.59
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  96.24°
Average Bifurcation Angle Remote :  91°
Fractal Dimension :  1.03

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