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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_295482 |
| Cell Name : | LPS_microglia_EV_1_Sec_2_Cell3 |
| Archive Name : | Kodali_Shetty |
| Species Name : | mouse |
| Strain : | C57BL/6J |
| Structural Domains : | Processes, Soma |
| Physical Integrity : | Processes Moderate |
| Morphological Attributes : | No Diameter, 3D, Angles |
| Min Age : | 70.0 days
|
| Max Age : | 70.0 days
|
| Gender : |
Male
|
| Min Weight : | Not reported
|
| Max Weight : | Not reported
|
| Development : | adult |
| Primary Brain Region : | hippocampus |
| Secondary Brain Region : | CA3 |
| Tertiary Brain Region : | stratum radiatum |
| Primary Cell Class : | Glia |
| Secondary Cell Class : | microglia |
| Tertiary Cell Class : | Iba1-positive |
| Original Format : | Neurolucida.dat |
| Experiment Protocol : | in vitro |
| Experimental Condition : | Lipopolysaccharide (LPS) + Extracellular vesicles (EV)-treated |
| Staining Method : | immunostaining |
| Slicing Direction : | coronal |
| Slice Thickness : | 30
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | oil |
| Magnification : | 100x |
| Reconstruction Method : | Neurolucida |
| Date of Deposition : | 2024-09-09 |
| Date of Upload : | 2025-01-27 |
| Persistence Vector : | LPS_microglia_EV_1_Sec_2_Cell3.pvec |
| Note : | This reconstruction was obtained from a mouse that received daily intraperitoneal injections of LPS (Escherichia coli serotype: 0111:B4; Sigma-Aldrich, St. Louis, MO, USA) dissolved in normal saline at a dose of 0.75 mg/kg for seven consecutive days (days 1-7). Starting from day 8, the mouse received three IN doses of hiPSC-NSCEVs over 6 days, with each dose separated by two days. |
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| Reference Article |
| Related Article Reference : | Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis in the hippocampus. |
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| Measurements |
| Soma Surface : |
26169.5 μm2 |
| Number of Stems : |
4 |
| Number of Bifurcations : |
23 |
| Number of Branches : |
50 |
| Overall Width : |
532.21 μm |
| Overall Height : |
371.59 μm |
| Overall Depth : |
5.25 μm |
| Average Diameter : |
0.86 μm |
| Total Length : |
3014.89 μm |
| Total Surface : |
8145.54 μm2 |
| Total Volume : |
1751.29 μm3 |
| Max Euclidean Distance : |
350.57 μm |
| Max Path Distance : |
701.39 μm |
| Max Branch Order : |
10 |
| Average Contraction : |
0.89 |
| Total Fragmentation : |
343 |
| Partition Asymmetry : |
0.54 |
| Average Rall's Ratio : |
2 |
| Average Bifurcation Angle Local : |
105.85° |
| Average Bifurcation Angle Remote : |
95.35° |
| Fractal Dimension : |
1.02 |
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