8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_265742
Cell Name :  IBA1_OMV_C3aRA_2b
Archive Name :  Vandenbroucke
Species Name :  mouse
Strain :  C57BL/6
Structural Domains :  Processes, No Soma
Physical Integrity :  Processes Moderate
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  84.0 days
Max Age :  112.0 days
Gender :  Male/Female
Min Weight :  20 grams
Max Weight :  25 grams
Development :  adult
Primary Brain Region :  hippocampus
Secondary Brain Region :  CA3
Tertiary Brain Region :  Not reported
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Iba1-positive
Original Format :  Imaris.ims
Experiment Protocol :  in vivo
Experimental Condition :  C3aR Antagonist + H. pylori outer membrane vesicles (OMVs)
Staining Method :  immunostaining
Slicing Direction :  coronal
Slice Thickness :  50  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  40x , 63x
Reconstruction Method :  Imaris
Date of Deposition :  2023-04-17
Date of Upload :  2023-05-25
Persistence Vector :  IBA1_OMV_C3aRA_2b.pvec
Note :  Mice were orally gavaged with H. pylori OMVs (20 microgram protein, 4 x 10^10 particles) simultaneously i.p. injected with 0.5% DMSO/C3aRA (1 mg/kg) once per day for 5 days and sacrificed at day 7.

Reference Article
Related Article Reference :  Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer''s disease pathogenesis via C3-C3aR signalling.

Measurements
Soma Surface :  N/A
Number of Stems :  2
Number of Bifurcations :  29
Number of Branches :  60
Overall Width :  20.09 μm
Overall Height :  48.95 μm
Overall Depth :  29.84 μm
Average Diameter :  1.18 μm
Total Length :  422.41 μm
Total Surface :  1578.71 μm2
Total Volume :  491.08 μm3
Max Euclidean Distance :  39.65 μm
Max Path Distance :  67.32 μm
Max Branch Order :  12
Average Contraction :  0.91
Total Fragmentation :  1010
Partition Asymmetry :  0.58
Average Rall's Ratio :  1.93
Average Bifurcation Angle Local :  61.8°
Average Bifurcation Angle Remote :  89.57°
Fractal Dimension :  1.03

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