8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_176919
Cell Name :  HO-2
Archive Name :  Milnerwood
Species Name :  mouse
Strain :  B6.Cg-Vps35tm1.1Mjff/J
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Complete
Morphological Attributes :  No Diameter, 2D, Angles
Min Age :  16.5 days
Max Age :  16.5 days
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  embryonic
Primary Brain Region :  neocortex
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  pyramidal
Tertiary Cell Class :  Not reported
Original Format :  Simple Neurite Tracer.traces
Experiment Protocol :  culture
Experimental Condition :  D620N knock-in
Staining Method :  green fluorescent protein
Slicing Direction :  Not applicable
Slice Thickness :  Not applicable
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  63x
Reconstruction Method :  Simple Neurite Tracer
Date of Deposition :  2021-10-20
Date of Upload :  2022-01-24
Persistence Vector :  HO-2.pvec

Reference Article
Related Article Reference :  Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition.

Measurements
Soma Surface :  583.38 μm2
Number of Stems :  6
Number of Bifurcations :  33
Number of Branches :  72
Overall Width :  414.16 μm
Overall Height :  569.92 μm
Overall Depth :  0 μm
Average Diameter :  0.25 μm
Total Length :  5322.81 μm
Total Surface :  4180.52 μm2
Total Volume :  261.28 μm3
Max Euclidean Distance :  553.68 μm
Max Path Distance :  680.51 μm
Max Branch Order :  8
Average Contraction :  0.92
Total Fragmentation :  4507
Partition Asymmetry :  0.47
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  50.33°
Average Bifurcation Angle Remote :  45.98°
Fractal Dimension :  1.02

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