8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_191979
Cell Name :  HC_App_NLGF-LPS5_24h_c
Archive Name :  Vandenbroucke
Species Name :  mouse
Strain :  App NL-G-F
Structural Domains :  Processes, No Soma
Physical Integrity :  Processes Moderate
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  5.0 months
Max Age :  5.8 months
Gender :  Male/Female
Min Weight :  20 grams
Max Weight :  30 grams
Development :  adult
Primary Brain Region :  hippocampus
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Iba1-positive
Original Format :  Imaris.ims
Experiment Protocol :  in vitro
Experimental Condition :  lipopolysaccharide injection
Staining Method :  immunostaining
Slicing Direction :  coronal
Slice Thickness :  50  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  40x
Reconstruction Method :  Imaris
Date of Deposition :  2022-05-06
Date of Upload :  2022-06-29
Persistence Vector :  HC_App_NLGF-LPS5_24h_c.pvec
Note :  LPS injections (1.0 mg/kg body weight, i.p.) were performed on days 0 and 7. This reconstruction was obtained 24h after the second LPS injection.

Reference Article
Related Article Reference :  Low-grade peripheral inflammation affects brain pathology in the AppNL-G-Fmouse model of Alzheimer's disease.

Measurements
Soma Surface :  N/A
Number of Stems :  1
Number of Bifurcations :  38
Number of Branches :  77
Overall Width :  15.88 μm
Overall Height :  48.85 μm
Overall Depth :  30.39 μm
Average Diameter :  1.01 μm
Total Length :  474.9 μm
Total Surface :  1501.22 μm2
Total Volume :  378.36 μm3
Max Euclidean Distance :  48.96 μm
Max Path Distance :  76.75 μm
Max Branch Order :  15
Average Contraction :  0.88
Total Fragmentation :  2271
Partition Asymmetry :  0.6
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  42.12°
Average Bifurcation Angle Remote :  85.06°
Fractal Dimension :  1.05

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