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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_265693 |
| Cell Name : | GFAP_OMV_C3aRA_2f |
| Archive Name : | Vandenbroucke |
| Species Name : | mouse |
| Strain : | C57BL/6 |
| Structural Domains : | Processes, No Soma |
| Physical Integrity : | Processes Moderate |
| Morphological Attributes : | No Diameter, 3D, Angles |
| Min Age : | 84.0 days
|
| Max Age : | 112.0 days
|
| Gender : |
Male/Female
|
| Min Weight : | 20 grams
|
| Max Weight : | 25 grams
|
| Development : | adult |
| Primary Brain Region : | hippocampus |
| Secondary Brain Region : | CA3 |
| Tertiary Brain Region : | Not reported |
| Primary Cell Class : | Glia |
| Secondary Cell Class : | astrocyte |
| Tertiary Cell Class : | GFAP-positive |
| Original Format : | Imaris.ims |
| Experiment Protocol : | in vivo |
| Experimental Condition : | C3aR Antagonist + H. pylori outer membrane vesicles (OMVs) |
| Staining Method : | immunostaining |
| Slicing Direction : | coronal |
| Slice Thickness : | 50
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | oil |
| Magnification : | 40x , 63x |
| Reconstruction Method : | Imaris |
| Date of Deposition : | 2023-04-17 |
| Date of Upload : | 2023-05-25 |
| Persistence Vector : | GFAP_OMV_C3aRA_2f.pvec |
| Note : | Mice were orally gavaged with H. pylori OMVs (20 microgram protein, 4 x 10^10 particles) simultaneously i.p. injected with 0.5% DMSO/C3aRA (1 mg/kg) once per day for 5 days and sacrificed at day 7. |
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| Reference Article |
| Related Article Reference : | Helicobacter pylori-derived outer membrane vesicles contribute to Alzheimer''s disease pathogenesis via C3-C3aR signalling. |
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| Measurements |
| Soma Surface : |
N/A |
| Number of Stems : |
2 |
| Number of Bifurcations : |
24 |
| Number of Branches : |
50 |
| Overall Width : |
10.27 μm |
| Overall Height : |
49.06 μm |
| Overall Depth : |
29.63 μm |
| Average Diameter : |
1.14 μm |
| Total Length : |
348.84 μm |
| Total Surface : |
1253.4 μm2 |
| Total Volume : |
382.54 μm3 |
| Max Euclidean Distance : |
35.18 μm |
| Max Path Distance : |
62.14 μm |
| Max Branch Order : |
13 |
| Average Contraction : |
0.93 |
| Total Fragmentation : |
953 |
| Partition Asymmetry : |
0.56 |
| Average Rall's Ratio : |
1.92 |
| Average Bifurcation Angle Local : |
57.69° |
| Average Bifurcation Angle Remote : |
70.55° |
| Fractal Dimension : |
1.03 |
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