8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_285414
Cell Name :  G2019S_3_GS-PAK_GFP_8_21
Archive Name :  Greggio
Species Name :  mouse
Strain :  LRRK2 G2019S
Structural Domains :  Neurites, Soma
Physical Integrity :  Neurites Complete
Morphological Attributes :  No Diameter, 2D, Angles
Min Age :  0.0 day
Max Age :  0.0 day
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  neonatal
Primary Brain Region :  neocortex
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  Not reported
Tertiary Cell Class :  Not reported
Original Format :  NeuronJ.ndf
Experiment Protocol :  culture
Experimental Condition :  PAK6
Staining Method :  green fluorescent protein, immunostaining
Slicing Direction :  Not applicable
Slice Thickness :  Not applicable
Tissue Shrinkage :  Not reported
Objective Type :  Not reported
Magnification :  Not reported
Reconstruction Method :  NeuronJ
Date of Deposition :  2019-01-14
Date of Upload :  2024-09-18
Persistence Vector :  G2019S_3_GS-PAK_GFP_8_21.pvec
Note :  Neurons were fixed using PFA 4% at DIV7 and subjected to analysis. Mice were transfected with Flag-PAK6 S531N.

Reference Article
Related Article Reference :  PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.

Measurements
Soma Surface :  106.29 μm2
Number of Stems :  9
Number of Bifurcations :  26
Number of Branches :  61
Overall Width :  70.03 μm
Overall Height :  35.8 μm
Overall Depth :  0.3 μm
Average Diameter :  1 μm
Total Length :  499.37 μm
Total Surface :  1568.83 μm2
Total Volume :  392.21 μm3
Max Euclidean Distance :  74.16 μm
Max Path Distance :  113.61 μm
Max Branch Order :  14
Average Contraction :  0.93
Total Fragmentation :  897
Partition Asymmetry :  0.69
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  92.74°
Average Bifurcation Angle Remote :  72.11°
Fractal Dimension :  1.03

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