8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_285469
Cell Name :  G2019S_3_GS-PAK_GFP_8_20
Archive Name :  Greggio
Species Name :  mouse
Strain :  LRRK2 G2019S
Structural Domains :  Neurites, Soma
Physical Integrity :  Neurites Complete
Morphological Attributes :  No Diameter, 2D, Angles
Min Age :  0.0 day
Max Age :  0.0 day
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  neonatal
Primary Brain Region :  neocortex
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  Not reported
Tertiary Cell Class :  Not reported
Original Format :  NeuronJ.ndf
Experiment Protocol :  culture
Experimental Condition :  PAK6
Staining Method :  green fluorescent protein, immunostaining
Slicing Direction :  Not applicable
Slice Thickness :  Not applicable
Tissue Shrinkage :  Not reported
Objective Type :  Not reported
Magnification :  Not reported
Reconstruction Method :  NeuronJ
Date of Deposition :  2019-01-14
Date of Upload :  2024-09-18
Persistence Vector :  G2019S_3_GS-PAK_GFP_8_20.pvec
Note :  Neurons were fixed using PFA 4% at DIV7 and subjected to analysis. Mice were transfected with Flag-PAK6 S531N.

Reference Article
Related Article Reference :  PAK6 Phosphorylates 14-3-3γ to Regulate Steady State Phosphorylation of LRRK2.

Measurements
Soma Surface :  139.03 μm2
Number of Stems :  13
Number of Bifurcations :  21
Number of Branches :  55
Overall Width :  63.78 μm
Overall Height :  19.65 μm
Overall Depth :  0.83 μm
Average Diameter :  1 μm
Total Length :  307.01 μm
Total Surface :  964.49 μm2
Total Volume :  241.12 μm3
Max Euclidean Distance :  43.81 μm
Max Path Distance :  51.68 μm
Max Branch Order :  3
Average Contraction :  0.92
Total Fragmentation :  538
Partition Asymmetry :  0.4
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  78.53°
Average Bifurcation Angle Remote :  63.32°
Fractal Dimension :  1.06

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