8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_139363
Cell Name :  FAT-99-d27-Pos3-1
Archive Name :  Heppner
Species Name :  mouse
Strain :  FracR-GFP+_APPPS1_TK-
Structural Domains :  Processes, No Soma
Physical Integrity :  Processes Complete
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  6.0 months
Max Age :  6.0 months
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  neocortex
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Not reported
Original Format :  Imaris.hoc
Experiment Protocol :  in vivo
Experimental Condition :  Control
Staining Method :  enhanced green fluorescent protein
Slicing Direction :  Not reported
Slice Thickness :  70  μm
Tissue Shrinkage :  Not reported
Objective Type :  IR-coated dipping intravital
Magnification :  20x
Reconstruction Method :  Imaris
Date of Deposition :  2020-07-03
Date of Upload :  2020-09-04
Persistence Vector :  FAT-99-d27-Pos3-1.pvec
Note :  Mice were irradiated and injected with tdRFP bone marrow cells. Four weeks after BM-transfer, a cranial window was installed and a mini-osmotic pump was implanted to deliver Ganciclovir for microglia ablation in TK+ animals. Imaging using 2-photon microscopy was started six days after surgery, and the mice were subsequently imaged once a week for six weeks. This reconstruction belongs to a control animal (TK-) 27 days after surgery.

Reference Article
Related Article Reference :  The Amyloid-beta rich CNS environment alters myeloid cell functionality independent of their origin.

Measurements
Soma Surface :  N/A
Number of Stems :  1
Number of Bifurcations :  60
Number of Branches :  121
Overall Width :  43.5 μm
Overall Height :  47.38 μm
Overall Depth :  31.86 μm
Average Diameter :  0.29 μm
Total Length :  581.53 μm
Total Surface :  535.5 μm2
Total Volume :  39.24 μm3
Max Euclidean Distance :  55.5 μm
Max Path Distance :  102.57 μm
Max Branch Order :  26
Average Contraction :  0.95
Total Fragmentation :  782
Partition Asymmetry :  0.71
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  76.82°
Average Bifurcation Angle Remote :  79.06°
Fractal Dimension :  1.03

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