8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_139314
Cell Name :  FAT-42-d48-Pos3-1
Archive Name :  Heppner
Species Name :  mouse
Strain :  FracR-GFP+_APPPS1_TK-
Structural Domains :  Processes, No Soma
Physical Integrity :  Processes Complete
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  6.0 months
Max Age :  6.0 months
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  neocortex
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Not reported
Original Format :  Imaris.hoc
Experiment Protocol :  in vivo
Experimental Condition :  Control
Staining Method :  enhanced green fluorescent protein
Slicing Direction :  Not reported
Slice Thickness :  70  μm
Tissue Shrinkage :  Not reported
Objective Type :  IR-coated dipping intravital
Magnification :  20x
Reconstruction Method :  Imaris
Date of Deposition :  2020-07-03
Date of Upload :  2020-09-04
Persistence Vector :  FAT-42-d48-Pos3-1.pvec
Note :  Mice were irradiated and injected with tdRFP bone marrow cells. Four weeks after BM-transfer, a cranial window was installed and a mini-osmotic pump was implanted to deliver Ganciclovir for microglia ablation in TK+ animals. Imaging using 2-photon microscopy was started six days after surgery, and the mice were subsequently imaged once a week for six weeks. This reconstruction belongs to a control animal (TK-) 48 days after surgery.

Reference Article
Related Article Reference :  The Amyloid-beta rich CNS environment alters myeloid cell functionality independent of their origin.

Measurements
Soma Surface :  N/A
Number of Stems :  1
Number of Bifurcations :  177
Number of Branches :  355
Overall Width :  34.69 μm
Overall Height :  59.06 μm
Overall Depth :  71.1 μm
Average Diameter :  0.31 μm
Total Length :  1544.08 μm
Total Surface :  1553.39 μm2
Total Volume :  138.98 μm3
Max Euclidean Distance :  77.52 μm
Max Path Distance :  146.77 μm
Max Branch Order :  38
Average Contraction :  0.94
Total Fragmentation :  2227
Partition Asymmetry :  0.71
Average Rall's Ratio :  2.53
Average Bifurcation Angle Local :  75.26°
Average Bifurcation Angle Remote :  68.55°
Fractal Dimension :  1.04

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