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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_140274 |
| Cell Name : | Exp_V1B-L5_cell5 |
| Archive Name : | Qiu |
| Species Name : | mouse |
| Strain : | C57BL/6J |
| Structural Domains : | Dendrites, Soma, No Axon |
| Physical Integrity : | Dendrites Complete |
| Morphological Attributes : | Diameter, 3D, Angles |
| Min Age : | 25.0 days
|
| Max Age : | 30.0 days
|
| Gender : |
Male/Female
|
| Min Weight : | Not reported
|
| Max Weight : | Not reported
|
| Development : | young adult |
| Primary Brain Region : | neocortex |
| Secondary Brain Region : | occipital |
| Tertiary Brain Region : | primary visual, layer 5 Binocular region |
| Primary Cell Class : | principal cell |
| Secondary Cell Class : | pyramidal |
| Tertiary Cell Class : | Not reported |
| Original Format : | Neurolucida.dat |
| Experiment Protocol : | in vivo |
| Experimental Condition : | Microglia depletion (PLX3397 gavage) |
| Staining Method : | biocytin |
| Slicing Direction : | coronal |
| Slice Thickness : | 350
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | dry |
| Magnification : | 20x |
| Reconstruction Method : | Neurolucida |
| Date of Deposition : | 2020-08-10 |
| Date of Upload : | 2020-10-05 |
| Persistence Vector : | Exp_V1B-L5_cell5.pvec |
| Note : | In order to cover the earlier cortical developmental stage, we started PLX3397 (PLX) gavage from P15 for a 14-day duration, ending at P28. PLX was dissolved in DMSO to a stock solution of 50 mg/ml. The stock solution was diluted in saline, which is then administered once per day through a gavage needle to achieve a dosage of 50 mg/kg. |
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| Reference Article |
| Related Article Reference : | Depletion of microglia in developing cortical circuits reveals its critical role in glutamatergic synapse development, functional connectivity, and critical period plasticity. |
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| Measurements |
| Soma Surface : |
1035.1 μm2 |
| Number of Stems : |
14 |
| Number of Bifurcations : |
59 |
| Number of Branches : |
132 |
| Overall Width : |
322.35 μm |
| Overall Height : |
755.48 μm |
| Overall Depth : |
168.07 μm |
| Average Diameter : |
0.73 μm |
| Total Length : |
8516.54 μm |
| Total Surface : |
19256.8 μm2 |
| Total Volume : |
3772.22 μm3 |
| Max Euclidean Distance : |
651.66 μm |
| Max Path Distance : |
831.16 μm |
| Max Branch Order : |
21 |
| Average Contraction : |
0.9 |
| Total Fragmentation : |
1093 |
| Partition Asymmetry : |
0.58 |
| Average Rall's Ratio : |
1.67 |
| Average Bifurcation Angle Local : |
78.55° |
| Average Bifurcation Angle Remote : |
68.91° |
| Fractal Dimension : |
1.03 |
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