8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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Details about selected cell
NeuroMorpho.Org ID :  NMO_271426
Cell Name :  E4F-301_2_D
Archive Name :  Seo
Species Name :  mouse
Strain :  ApoE4/ApoE4
Structural Domains :  Processes, Soma
Physical Integrity :  Processes Moderate
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  280.0 days
Max Age :  280.0 days
Gender :  Male
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  hippocampus
Secondary Brain Region :  dentate gyrus
Tertiary Brain Region :  molecular layer
Primary Cell Class :  Glia
Secondary Cell Class :  astrocyte
Tertiary Cell Class :  GFAP-positive
Original Format :  Simple Neurite Tracer.traces
Experiment Protocol :  in vivo
Experimental Condition :  short-term antibiotic (ABX) treatment early in life
Staining Method :  immunostaining
Slicing Direction :  coronal
Slice Thickness :  50  μm
Tissue Shrinkage :  Not reported
Objective Type :  dry
Magnification :  40x
Reconstruction Method :  Simple Neurite Tracer
Date of Deposition :  2023-09-04
Date of Upload :  2023-09-13
Persistence Vector :  E4F-301_2_D.pvec
Note :  Pups assigned to the ABX treatment group were gavaged with 100 microliters of an antibiotic cocktail that contained 4 mg/mL kanamycin, 0.35 mg/mL gentamicin; 8500 U/mL colistin, 2.15 mg/mL metronidazole, and 0.45 mg/mL vancomycin. Gavage occurred daily from postnatal day 16 to 22 using animal feeding needles. This reconstruction was obtained from Tau-negative mice that lack a P301S transgene.

Reference Article
Related Article Reference :  ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy.

Measurements
Soma Surface :  12.4 μm2
Number of Stems :  4
Number of Bifurcations :  2
Number of Branches :  8
Overall Width :  50.01 μm
Overall Height :  32.84 μm
Overall Depth :  7 μm
Average Diameter :  0.25 μm
Total Length :  185.53 μm
Total Surface :  145.71 μm2
Total Volume :  9.11 μm3
Max Euclidean Distance :  29.45 μm
Max Path Distance :  35.66 μm
Max Branch Order :  1
Average Contraction :  0.77
Total Fragmentation :  463
Partition Asymmetry :  0
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  68.46°
Average Bifurcation Angle Remote :  36.68°
Fractal Dimension :  1.09

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