8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_270452
Cell Name :  E3F-136_2_D
Archive Name :  Seo
Species Name :  mouse
Strain :  P301S::ApoE3/ApoE3
Structural Domains :  Processes, Soma
Physical Integrity :  Processes Moderate
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  280.0 days
Max Age :  280.0 days
Gender :  Male
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  hippocampus
Secondary Brain Region :  dentate gyrus
Tertiary Brain Region :  molecular layer
Primary Cell Class :  Glia
Secondary Cell Class :  astrocyte
Tertiary Cell Class :  GFAP-positive
Original Format :  Simple Neurite Tracer.traces
Experiment Protocol :  in vivo
Experimental Condition :  short-term antibiotic (ABX) treatment early in life
Staining Method :  immunostaining
Slicing Direction :  coronal
Slice Thickness :  50  μm
Tissue Shrinkage :  Not reported
Objective Type :  dry
Magnification :  40x
Reconstruction Method :  Simple Neurite Tracer
Date of Deposition :  2023-09-04
Date of Upload :  2023-09-13
Persistence Vector :  E3F-136_2_D.pvec
Note :  Pups assigned to the ABX treatment group were gavaged with 100 microliters of an antibiotic cocktail that contained 4 mg/mL kanamycin, 0.35 mg/mL gentamicin; 8500 U/mL colistin, 2.15 mg/mL metronidazole, and 0.45 mg/mL vancomycin. Gavage occurred daily from postnatal day 16 to 22 using animal feeding needles. This reconstruction was obtained from Tau-negative mice that lack a P301S transgene.

Reference Article
Related Article Reference :  ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy.

Measurements
Soma Surface :  12.48 μm2
Number of Stems :  1
Number of Bifurcations :  9
Number of Branches :  19
Overall Width :  37.99 μm
Overall Height :  25.12 μm
Overall Depth :  6 μm
Average Diameter :  0.25 μm
Total Length :  174.11 μm
Total Surface :  136.75 μm2
Total Volume :  8.55 μm3
Max Euclidean Distance :  31.29 μm
Max Path Distance :  43.27 μm
Max Branch Order :  6
Average Contraction :  0.86
Total Fragmentation :  457
Partition Asymmetry :  0.57
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  66.36°
Average Bifurcation Angle Remote :  58.4°
Fractal Dimension :  1.07

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