8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_158898
Cell Name :  CuRD5m40x-Iba1555BF11ctx3J20Cu_c
Archive Name :  Lim_Kitazawa
Species Name :  mouse
Strain :  PDGF-hAPPSw,Ind J20
Structural Domains :  Processes, No Soma
Physical Integrity :  Processes Complete
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  6.0 months
Max Age :  6.0 months
Gender :  Female
Min Weight :  25 grams
Max Weight :  25 grams
Development :  adult
Primary Brain Region :  neocortex
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Iba1-positive
Original Format :  Imaris.ims
Experiment Protocol :  in vitro
Experimental Condition :  chronic copper-spiked water exposure
Staining Method :  immunostaining
Slicing Direction :  coronal
Slice Thickness :  40  μm
Tissue Shrinkage :  Not reported
Objective Type :  dry
Magnification :  40x
Reconstruction Method :  Imaris
Date of Deposition :  2021-05-20
Date of Upload :  2021-07-07
Persistence Vector :  CuRD5m40x-Iba1555BF11ctx3J20Cu_c.pvec
Note :  Mice were exposed to 1.3 ppm Cu-containing Milli-Q water (Cu) for 5 months, starting at 1 month of age, and were analyzed at 6-month old when mice were at an early stage of pathological development. Reconstructions were obtained from a coronal section (Bregma: -2.54mm).

Reference Article
Related Article Reference :  Chronic copper exposure directs microglia towards degenerative expression signatures in wild-type and J20 mouse model of Alzheimer's disease.

Measurements
Soma Surface :  N/A
Number of Stems :  1
Number of Bifurcations :  5
Number of Branches :  11
Overall Width :  3.36 μm
Overall Height :  28.68 μm
Overall Depth :  18.82 μm
Average Diameter :  1.14 μm
Total Length :  87.96 μm
Total Surface :  312.41 μm2
Total Volume :  93.54 μm3
Max Euclidean Distance :  16.85 μm
Max Path Distance :  37.5 μm
Max Branch Order :  5
Average Contraction :  0.88
Total Fragmentation :  228
Partition Asymmetry :  0.8
Average Rall's Ratio :  2.07
Average Bifurcation Angle Local :  99.33°
Average Bifurcation Angle Remote :  106.06°
Fractal Dimension :  1.05

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