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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_158889 |
| Cell Name : | CuRD5m40x-Iba1555BF11ctx3J20Cu_a |
| Archive Name : | Lim_Kitazawa |
| Species Name : | mouse |
| Strain : | PDGF-hAPPSw,Ind J20 |
| Structural Domains : | Processes, No Soma |
| Physical Integrity : | Processes Complete |
| Morphological Attributes : | No Diameter, 3D, Angles |
| Min Age : | 6.0 months
|
| Max Age : | 6.0 months
|
| Gender : |
Female
|
| Min Weight : | 25 grams
|
| Max Weight : | 25 grams
|
| Development : | adult |
| Primary Brain Region : | neocortex |
| Secondary Brain Region : | Not reported |
| Tertiary Brain Region : | Not reported |
| Primary Cell Class : | Glia |
| Secondary Cell Class : | microglia |
| Tertiary Cell Class : | Iba1-positive |
| Original Format : | Imaris.ims |
| Experiment Protocol : | in vitro |
| Experimental Condition : | chronic copper-spiked water exposure |
| Staining Method : | immunostaining |
| Slicing Direction : | coronal |
| Slice Thickness : | 40
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | dry |
| Magnification : | 40x |
| Reconstruction Method : | Imaris |
| Date of Deposition : | 2021-05-20 |
| Date of Upload : | 2021-07-07 |
| Persistence Vector : | CuRD5m40x-Iba1555BF11ctx3J20Cu_a.pvec |
| Note : | Mice were exposed to 1.3 ppm Cu-containing Milli-Q water (Cu) for 5 months, starting at 1 month of age, and were analyzed at 6-month old when mice were at an early stage of pathological development. Reconstructions were obtained from a coronal section (Bregma: -2.54mm). |
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| Reference Article |
| Related Article Reference : | Chronic copper exposure directs microglia towards degenerative expression signatures in wild-type and J20 mouse model of Alzheimer's disease. |
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| Measurements |
| Soma Surface : |
N/A |
| Number of Stems : |
2 |
| Number of Bifurcations : |
5 |
| Number of Branches : |
12 |
| Overall Width : |
5.32 μm |
| Overall Height : |
12.52 μm |
| Overall Depth : |
25.99 μm |
| Average Diameter : |
1.36 μm |
| Total Length : |
78.04 μm |
| Total Surface : |
325.93 μm2 |
| Total Volume : |
131.72 μm3 |
| Max Euclidean Distance : |
18.88 μm |
| Max Path Distance : |
20.53 μm |
| Max Branch Order : |
4 |
| Average Contraction : |
0.86 |
| Total Fragmentation : |
192 |
| Partition Asymmetry : |
0.53 |
| Average Rall's Ratio : |
1.8 |
| Average Bifurcation Angle Local : |
44.16° |
| Average Bifurcation Angle Remote : |
58.7° |
| Fractal Dimension : |
1.07 |
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