8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_191971
Cell Name :  Ctx_APP_NLGF_LPS_2week_3_a
Archive Name :  Vandenbroucke
Species Name :  mouse
Strain :  App NL-G-F
Structural Domains :  Processes, No Soma
Physical Integrity :  Processes Moderate
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  5.0 months
Max Age :  5.8 months
Gender :  Male/Female
Min Weight :  20 grams
Max Weight :  30 grams
Development :  adult
Primary Brain Region :  neocortex
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Iba1-positive
Original Format :  Imaris.ims
Experiment Protocol :  in vitro
Experimental Condition :  lipopolysaccharide injection
Staining Method :  immunostaining
Slicing Direction :  coronal
Slice Thickness :  50  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  40x
Reconstruction Method :  Imaris
Date of Deposition :  2022-05-06
Date of Upload :  2022-06-29
Persistence Vector :  Ctx_APP_NLGF_LPS_2week_3_a.pvec
Note :  LPS injections (1.0 mg/kg body weight, i.p.) were performed on days 0 and 7. This reconstruction was obtained 2 weeks after the second LPS injection.

Reference Article
Related Article Reference :  Low-grade peripheral inflammation affects brain pathology in the AppNL-G-Fmouse model of Alzheimer's disease.

Measurements
Soma Surface :  N/A
Number of Stems :  2
Number of Bifurcations :  33
Number of Branches :  68
Overall Width :  10.92 μm
Overall Height :  48.09 μm
Overall Depth :  34.34 μm
Average Diameter :  1.16 μm
Total Length :  410.29 μm
Total Surface :  1514.1 μm2
Total Volume :  479.12 μm3
Max Euclidean Distance :  36.85 μm
Max Path Distance :  45.59 μm
Max Branch Order :  10
Average Contraction :  0.92
Total Fragmentation :  1123
Partition Asymmetry :  0.57
Average Rall's Ratio :  2.03
Average Bifurcation Angle Local :  63.63°
Average Bifurcation Angle Remote :  84.78°
Fractal Dimension :  1.03

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