8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_191934
Cell Name :  Ctx_APP_NLGF_LPS_24h_4_b
Archive Name :  Vandenbroucke
Species Name :  mouse
Strain :  App NL-G-F
Structural Domains :  Processes, No Soma
Physical Integrity :  Processes Moderate
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  5.0 months
Max Age :  5.8 months
Gender :  Male/Female
Min Weight :  20 grams
Max Weight :  30 grams
Development :  adult
Primary Brain Region :  neocortex
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Iba1-positive
Original Format :  Imaris.ims
Experiment Protocol :  in vitro
Experimental Condition :  lipopolysaccharide injection
Staining Method :  immunostaining
Slicing Direction :  coronal
Slice Thickness :  50  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  40x
Reconstruction Method :  Imaris
Date of Deposition :  2022-05-06
Date of Upload :  2022-06-29
Persistence Vector :  Ctx_APP_NLGF_LPS_24h_4_b.pvec
Note :  LPS injections (1.0 mg/kg body weight, i.p.) were performed on days 0 and 7. This reconstruction was obtained 24h after the second LPS injection.

Reference Article
Related Article Reference :  Low-grade peripheral inflammation affects brain pathology in the AppNL-G-Fmouse model of Alzheimer's disease.

Measurements
Soma Surface :  N/A
Number of Stems :  1
Number of Bifurcations :  18
Number of Branches :  37
Overall Width :  13.79 μm
Overall Height :  37.41 μm
Overall Depth :  21.12 μm
Average Diameter :  1.17 μm
Total Length :  225.25 μm
Total Surface :  822.52 μm2
Total Volume :  255.3 μm3
Max Euclidean Distance :  23.95 μm
Max Path Distance :  34.54 μm
Max Branch Order :  7
Average Contraction :  0.92
Total Fragmentation :  606
Partition Asymmetry :  0.65
Average Rall's Ratio :  1.93
Average Bifurcation Angle Local :  45.8°
Average Bifurcation Angle Remote :  79.42°
Fractal Dimension :  1.04

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