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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_159950 |
| Cell Name : | CUP49 |
| Archive Name : | Zhan_Kipp |
| Species Name : | mouse |
| Strain : | C57BL/6J |
| Structural Domains : | Processes, Soma |
| Physical Integrity : | Processes Moderate |
| Morphological Attributes : | No Diameter, 3D, Angles |
| Min Age : | 287.0 days
|
| Max Age : | 287.0 days
|
| Gender : |
Male
|
| Min Weight : | Not reported
|
| Max Weight : | Not reported
|
| Development : | adult |
| Primary Brain Region : | neocortex |
| Secondary Brain Region : | anterior cingulate |
| Tertiary Brain Region : | layer 5 |
| Primary Cell Class : | Glia |
| Secondary Cell Class : | microglia |
| Tertiary Cell Class : | Iba1-positive |
| Original Format : | Neurolucida.dat |
| Experiment Protocol : | in vitro |
| Experimental Condition : | cuprizone intoxication |
| Staining Method : | immunostaining |
| Slicing Direction : | coronal |
| Slice Thickness : | 5
μm |
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | Not reported |
| Magnification : | Not reported
|
| Reconstruction Method : | Neurolucida |
| Date of Deposition : | 2021-07-02 |
| Date of Upload : | 2021-07-26 |
| Persistence Vector : | CUP49.pvec |
| Note : | Reconstructions were obtained from cortical layers 5-6 where microglial morphology should not be biased by the dense network of axonal bundles in the corpus callosum. Cup-Recov group; mice were intoxicated with a diet containing cuprizone (bis(cyclohexanone)oxaldihydrazone) mixed into ground standard rodent chow for 5 weeks (first 2 weeks 0.2% following by 3 weeks 0.25%) to induce acute demyelination, followed by 28 weeks standard pelleted rodent chow allowing for long-term recovery. |
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| Reference Article |
| Related Article Reference : | Focal white matter lesions induce long-lasting axonal degeneration, neuroinflammation and behavioral deficits. |
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| Measurements |
| Soma Surface : |
64.53 μm2 |
| Number of Stems : |
4 |
| Number of Bifurcations : |
2 |
| Number of Branches : |
8 |
| Overall Width : |
5.53 μm |
| Overall Height : |
21.06 μm |
| Overall Depth : |
9.35 μm |
| Average Diameter : |
0.48 μm |
| Total Length : |
58.44 μm |
| Total Surface : |
86.14 μm2 |
| Total Volume : |
10.48 μm3 |
| Max Euclidean Distance : |
14.37 μm |
| Max Path Distance : |
17.56 μm |
| Max Branch Order : |
1 |
| Average Contraction : |
0.83 |
| Total Fragmentation : |
74 |
| Partition Asymmetry : |
0 |
| Average Rall's Ratio : |
1.86 |
| Average Bifurcation Angle Local : |
54.34° |
| Average Bifurcation Angle Remote : |
92.89° |
| Fractal Dimension : |
1.07 |
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