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| Details about selected cell |
| NeuroMorpho.Org ID : | NMO_301496 |
| Cell Name : | CC8i-2d-30N-38A-TUJ1-P4-tracings_c |
| Archive Name : | Apokotou |
| Species Name : | human |
| Strain : | Not reported |
| Structural Domains : | Neurites, Soma |
| Physical Integrity : | Neurites Complete |
| Morphological Attributes : | No Diameter, 2D, Angles |
| Min Age : | 40.0 years
|
| Max Age : | 49.0 years
|
| Gender : |
Male
|
| Min Weight : | Not reported
|
| Max Weight : | Not reported
|
| Development : | adult |
| Primary Brain Region : | brainstem |
| Secondary Brain Region : | midbrain |
| Tertiary Brain Region : | ventral |
| Primary Cell Class : | principal cell |
| Secondary Cell Class : | induced pluripotent stem cell-(iPSC)-derived |
| Tertiary Cell Class : | tyrosine hydroxylase (TH) positive, dopaminergic |
| Original Format : | NeuronJ.ndf |
| Experiment Protocol : | in vitro |
| Experimental Condition : | A53T (Parkinson's) astrocytes |
| Staining Method : | immunostaining |
| Slicing Direction : | Not applicable |
| Slice Thickness : | Not applicable
|
| Tissue Shrinkage : |
Not reported
|
| Objective Type : | oil |
| Magnification : | 63x |
| Reconstruction Method : | NeuronJ |
| Date of Deposition : | 2025-07-01 |
| Date of Upload : | 2025-08-26 |
| Persistence Vector : | CC8i-2d-30N-38A-TUJ1-P4-tracings_c.pvec |
| Note : | This reconstruction was obtained from a co-culture of healthy neurons (Hn) with Parkinson’s disease astrocytes (A53t, PDa). |
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| Reference Article |
| Related Article Reference : | Proteostasis dysregulation in p.A53T-α-Synuclein iPSC-derived astrocytes exacerbates neurodegeneration in a Parkinson’s disease model with Lewy-like pathology |
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| Measurements |
| Soma Surface : |
17661.2 μm2 |
| Number of Stems : |
3 |
| Number of Bifurcations : |
3 |
| Number of Branches : |
9 |
| Overall Width : |
673.54 μm |
| Overall Height : |
348.76 μm |
| Overall Depth : |
0 μm |
| Average Diameter : |
1 μm |
| Total Length : |
1455.28 μm |
| Total Surface : |
4571.89 μm2 |
| Total Volume : |
1142.97 μm3 |
| Max Euclidean Distance : |
532.04 μm |
| Max Path Distance : |
564.86 μm |
| Max Branch Order : |
2 |
| Average Contraction : |
0.96 |
| Total Fragmentation : |
261 |
| Partition Asymmetry : |
0.33 |
| Average Rall's Ratio : |
2 |
| Average Bifurcation Angle Local : |
73.21° |
| Average Bifurcation Angle Remote : |
109.75° |
| Fractal Dimension : |
1 |
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0
