8.6.88 - Released: 2025-08-26 - Content: 278255 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_301184
Cell Name :  CC11-2d-47N-47A-TUJ1-8bit-P4_g
Archive Name :  Apokotou
Species Name :  human
Strain :  Not reported
Structural Domains :  Neurites, Soma
Physical Integrity :  Neurites Complete
Morphological Attributes :  No Diameter, 2D, Angles
Min Age :  40.0 years
Max Age :  49.0 years
Gender :  Male
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  brainstem
Secondary Brain Region :  midbrain
Tertiary Brain Region :  ventral
Primary Cell Class :  principal cell
Secondary Cell Class :  induced pluripotent stem cell-(iPSC)-derived
Tertiary Cell Class :  tyrosine hydroxylase (TH) positive, dopaminergic
Original Format :  NeuronJ.ndf
Experiment Protocol :  in vitro
Experimental Condition :  A53T (Parkinson's) neurons with A53T (Parkinson's) astrocytes
Staining Method :  immunostaining
Slicing Direction :  Not applicable
Slice Thickness :  Not applicable
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  63x
Reconstruction Method :  NeuronJ
Date of Deposition :  2025-07-01
Date of Upload :  2025-08-26
Persistence Vector :  CC11-2d-47N-47A-TUJ1-8bit-P4_g.pvec
Note :  This reconstruction was obtained from a co-culture of Parkinson’s disease neurons (A53t, PDn) with Parkinson’s disease astrocytes (A53t, PDa).

Reference Article
Related Article Reference :  Proteostasis dysregulation in p.A53T-α-Synuclein iPSC-derived astrocytes exacerbates neurodegeneration in a Parkinson’s disease model with Lewy-like pathology

Measurements
Soma Surface :  169.05 μm2
Number of Stems :  2
Number of Bifurcations :  1
Number of Branches :  4
Overall Width :  51.92 μm
Overall Height :  19.2 μm
Overall Depth :  0 μm
Average Diameter :  1 μm
Total Length :  80.76 μm
Total Surface :  253.71 μm2
Total Volume :  63.43 μm3
Max Euclidean Distance :  42.32 μm
Max Path Distance :  45.72 μm
Max Branch Order :  1
Average Contraction :  0.95
Total Fragmentation :  140
Partition Asymmetry :  0
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  35.48°
Average Bifurcation Angle Remote :  84.1°
Fractal Dimension :  1.02

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