8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_171342
Cell Name :  C1-M_SP12wtD80THMAP-S1_a
Archive Name :  Consiglio
Species Name :  human
Strain :  Not applicable
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Moderate
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  63.0 years
Max Age :  63.0 years
Gender :  Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  Not reported
Secondary Brain Region :  Not reported
Tertiary Brain Region :  Not reported
Primary Cell Class :  principal cell
Secondary Cell Class :  induced pluripotent stem cell-(iPSC)-derived
Tertiary Cell Class :  tyrosine hydroxylase (TH) positive
Original Format :  NeuronJ.ndf
Experiment Protocol :  culture
Experimental Condition :  G2019S mutation in LRRK2 gene corrected
Staining Method :  immunostaining
Slicing Direction :  Not applicable
Slice Thickness :  Not applicable
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  63x
Reconstruction Method :  NeuronJ
Date of Deposition :  2021-08-25
Date of Upload :  2021-12-21
Persistence Vector :  C1-M_SP12wtD80THMAP-S1_a.pvec
Note :  This reconstruction was obtained 80 days after differentiation.

Reference Article
Related Article Reference :  Parkinson's disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration.

Measurements
Soma Surface :  353.48 μm2
Number of Stems :  2
Number of Bifurcations :  9
Number of Branches :  20
Overall Width :  257.37 μm
Overall Height :  573.76 μm
Overall Depth :  3.75 μm
Average Diameter :  1 μm
Total Length :  1507.47 μm
Total Surface :  4735.86 μm2
Total Volume :  1183.96 μm3
Max Euclidean Distance :  495.38 μm
Max Path Distance :  584.32 μm
Max Branch Order :  5
Average Contraction :  0.94
Total Fragmentation :  270
Partition Asymmetry :  0.59
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  75.34°
Average Bifurcation Angle Remote :  108.32°
Fractal Dimension :  1.01

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