8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_285800
Cell Name :  Aged_mice_VAC-H7N710_74-CA1-9
Archive Name :  Hosseini
Species Name :  mouse
Strain :  C57BL/6JRj
Structural Domains :  Processes, No Soma
Physical Integrity :  Processes Moderate
Morphological Attributes :  Diameter, 3D, Angles
Min Age :  15.0 months
Max Age :  15.0 months
Gender :  Female
Min Weight :  29 grams
Max Weight :  32 grams
Development :  old
Primary Brain Region :  hippocampus
Secondary Brain Region :  CA1
Tertiary Brain Region :  stratum radiatum
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Iba1-positive
Original Format :  Imaris.hoc
Experiment Protocol :  in vitro
Experimental Condition :  formalin-inactivated H7N7 IAV vaccine + cyclic di-AMP adjuvant (VAC)
Staining Method :  immunostaining
Slicing Direction :  coronal
Slice Thickness :  20  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  40x
Reconstruction Method :  Imaris
Date of Deposition :  2024-07-14
Date of Upload :  2024-09-30
Persistence Vector :  Aged_mice_VAC-H7N710_74-CA1-9.pvec
Note :  This reconstruction was obtained from a mouse immunized intranasally three times at 14-day intervals with a formalin-inactivated H7N7 vaccine containing a cyclic di-AMP adjuvant (VAC), after 10 days post-infection. The immunized animals were administered intranasally a dose of 8.4 micrograms per mouse of formalin-inactivated H7N7 IAV vaccine with 10 micrograms/microliter of mucosal adjuvant cyclic di-AMP in 20 microliters Ampuwa as immune priming.

Reference Article
Related Article Reference :  Influenza vaccine is able to prevent neuroinflammation triggered by H7N7 IAV infection.

Measurements
Soma Surface :  N/A
Number of Stems :  1
Number of Bifurcations :  143
Number of Branches :  287
Overall Width :  18.09 μm
Overall Height :  35.59 μm
Overall Depth :  43.21 μm
Average Diameter :  1 μm
Total Length :  922.27 μm
Total Surface :  2897.41 μm2
Total Volume :  724.35 μm3
Max Euclidean Distance :  32.44 μm
Max Path Distance :  60.04 μm
Max Branch Order :  20
Average Contraction :  0.9
Total Fragmentation :  6561
Partition Asymmetry :  0.58
Average Rall's Ratio :  2
Average Bifurcation Angle Local :  51.17°
Average Bifurcation Angle Remote :  61.07°
Fractal Dimension :  1.05

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