|
Details about selected cell |
NeuroMorpho.Org ID : | NMO_123518 |
Cell Name : | A20CGRP_Iba1-Z_125-1 |
Archive Name : | Morara |
Species Name : | mouse |
Strain : | C57BL/6J |
Structural Domains : | Processes, Soma |
Physical Integrity : | Processes Moderate |
Morphological Attributes : | Diameter, 2D, Angles |
Min Age : | 1.8 months
|
Max Age : | 2.0 months
|
Gender : |
Female
|
Min Weight : | 20 grams
|
Max Weight : | 23 grams
|
Development : | young adult |
Primary Brain Region : | spinal cord |
Secondary Brain Region : | L6 |
Tertiary Brain Region : | Not reported |
Primary Cell Class : | Glia |
Secondary Cell Class : | microglia |
Tertiary Cell Class : | Iba1-positive |
Original Format : | Neuronstudio.swc |
Experiment Protocol : | in vitro |
Experimental Condition : | Experimental autoimmune encephalomyelitis Calcitonin gene-related peptide (CGRP)-treated |
Staining Method : | immunostaining |
Slicing Direction : | coronal |
Slice Thickness : | 10
μm |
Tissue Shrinkage : |
Not reported
|
Objective Type : | oil |
Magnification : | 63x |
Reconstruction Method : | NeuronStudio |
Date of Deposition : | 2019-08-16 |
Date of Upload : | 2019-12-13 |
Persistence Vector : | A20CGRP_Iba1-Z_125-1.pvec |
Note : | Immunized by subcutaneous injections with 300 ul of 200 ug Myelin Oligodendrocyte Glycoprotein (MOG)35-55 in incomplete Complete Freunds Adjuvant containing 8 mg/ml Mycobacterium tuberculosis. Pertussis toxin (500 ng) injected on day of immunization + two days later (Sardi et al 2014). CGRP osmotically administered (50 pmol/h) by intrathecal catheter. Reconstructions performed at 16 dpi (after 14 days of delivery). |
|
|
Reference Article |
Related Article Reference : | Calcitonin gene-related peptide decreases IL-1beta, IL-6 as well as Ym1, Arg1, CD163 expression in a brain tissue context-dependent manner while amelioratingexperimental autoimmune encephalomyelitis. |
|
|
|
Measurements |
Soma Surface : |
3.58 μm2 |
Number of Stems : |
3 |
Number of Bifurcations : |
2 |
Number of Branches : |
7 |
Overall Width : |
0.98 μm |
Overall Height : |
10.16 μm |
Overall Depth : |
3.76 μm |
Average Diameter : |
0.45 μm |
Total Length : |
21.21 μm |
Total Surface : |
34.96 μm2 |
Total Volume : |
5.89 μm3 |
Max Euclidean Distance : |
6.34 μm |
Max Path Distance : |
7.74 μm |
Max Branch Order : |
2 |
Average Contraction : |
0.94 |
Total Fragmentation : |
52 |
Partition Asymmetry : |
0.5 |
Average Rall's Ratio : |
23.56 |
Average Bifurcation Angle Local : |
52.6° |
Average Bifurcation Angle Remote : |
60.96° |
Fractal Dimension : |
1.04 |
|
|
|
|
|