8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_161366
Cell Name :  20180102_sample_1
Archive Name :  Tolias
Species Name :  mouse
Strain :  Pvalb-Cre;Ai9
Structural Domains :  Dendrites, Soma, No Axon
Physical Integrity :  Dendrites Complete
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  75.0 days
Max Age :  75.0 days
Gender :  Male/Female
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  neocortex
Secondary Brain Region :  frontal
Tertiary Brain Region :  primary motor, layer 5
Primary Cell Class :  principal cell
Secondary Cell Class :  pyramidal
Tertiary Cell Class :  Excitatory, Parvalbumin (PV)-negative, Extratelencephalic (ET)
Original Format :  Neurolucida.swc
Experiment Protocol :  in vitro
Experimental Condition :  Control
Staining Method :  biocytin
Slicing Direction :  coronal
Slice Thickness :  300  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  100x
Reconstruction Method :  Neurolucida
Date of Deposition :  2020-01-24
Date of Upload :  2021-08-05
Persistence Vector :  20180102_sample_1.pvec
Note :  Large big-tufted cells with the apical dendrite often bifurcating close to the soma, suggesting that these were corticospinal cells. They had bigger hyperpolarization sag, lower input resistance, and smaller AP width, compared to the L5 IT neurons. We did not observe consistent morpho-electric differences between the four ET types, apart from L5 ET_1 being located deeper than the rest, but they may have different projection targets.

Reference Article
Related Article Reference :  Phenotypic variation of transcriptomic cell types in mouse motor cortex.

Measurements
Soma Surface :  1322.44 μm2
Number of Stems :  5
Number of Bifurcations :  50
Number of Branches :  105
Overall Width :  269.51 μm
Overall Height :  827.37 μm
Overall Depth :  75.5 μm
Average Diameter :  0.41 μm
Total Length :  6995.99 μm
Total Surface :  9037.18 μm2
Total Volume :  1952.52 μm3
Max Euclidean Distance :  731.48 μm
Max Path Distance :  945.27 μm
Max Branch Order :  19
Average Contraction :  0.8
Total Fragmentation :  3085
Partition Asymmetry :  0.54
Average Rall's Ratio :  1.19
Average Bifurcation Angle Local :  80.55°
Average Bifurcation Angle Remote :  67.49°
Fractal Dimension :  1.06

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