8.6.82 - Released: 2025-05-21 - Content: 275062 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_283294
Cell Name :  16p11_THC_at_P51_NAc
Archive Name :  Kamiya
Species Name :  mouse
Strain :  16p11dup;Cx3cr1CreER/+;Cnr1flox/flox
Structural Domains :  Processes, Soma
Physical Integrity :  Processes Complete
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  51.0 days
Max Age :  51.0 days
Gender :  Male
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  basal ganglia
Secondary Brain Region :  nucleus accumbens
Tertiary Brain Region :  Not reported
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Iba1-positive
Original Format :  Imaris.ims
Experiment Protocol :  in vitro
Experimental Condition :  16p11.2 duplication + Tetrahydrocannabinol (THC) exposure
Staining Method :  Alexa Fluor 488, immunostaining
Slicing Direction :  coronal
Slice Thickness :  100  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  100x
Reconstruction Method :  Imaris
Date of Deposition :  2024-05-24
Date of Upload :  2024-06-25
Persistence Vector :  16p11_THC_at_P51_NAc.pvec
Note :  This reconstruction was obtained from a mouse treated daily with a single subcutaneous injection (s.c.) of THC (8 mg/kg) during adolescence (P30-P51).

Reference Article
Related Article Reference :  Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11.2 duplication.

Measurements
Soma Surface :  149.6 μm2
Number of Stems :  6
Number of Bifurcations :  96
Number of Branches :  198
Overall Width :  5.88 μm
Overall Height :  62.99 μm
Overall Depth :  60.57 μm
Average Diameter :  0.76 μm
Total Length :  917.95 μm
Total Surface :  2189.33 μm2
Total Volume :  434.04 μm3
Max Euclidean Distance :  48.28 μm
Max Path Distance :  81.34 μm
Max Branch Order :  13
Average Contraction :  0.89
Total Fragmentation :  2855
Partition Asymmetry :  0.62
Average Rall's Ratio :  1.91
Average Bifurcation Angle Local :  94.4°
Average Bifurcation Angle Remote :  87.67°
Fractal Dimension :  1.05

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