8.6.79 - Released: 2025-04-16 - Content: 273841 cells
Morphology File (Standardized)
Morphology File (Original)
Log File (Standardized)
Log File (Original)



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NeuroMorpho.Org ID :  NMO_283289
Cell Name :  16p11-THC-at-P72_mPFC
Archive Name :  Kamiya
Species Name :  mouse
Strain :  16p11dup;Cx3cr1CreER/+;Cnr1flox/flox
Structural Domains :  Processes, No Soma
Physical Integrity :  Processes Complete
Morphological Attributes :  No Diameter, 3D, Angles
Min Age :  72.0 days
Max Age :  72.0 days
Gender :  Male
Min Weight :  Not reported
Max Weight :  Not reported
Development :  adult
Primary Brain Region :  neocortex
Secondary Brain Region :  medial prefrontal
Tertiary Brain Region :  Not reported
Primary Cell Class :  Glia
Secondary Cell Class :  microglia
Tertiary Cell Class :  Iba1-positive
Original Format :  Imaris.ims
Experiment Protocol :  in vitro
Experimental Condition :  16p11.2 duplication + Tetrahydrocannabinol (THC) exposure
Staining Method :  Alexa Fluor 488, immunostaining
Slicing Direction :  coronal
Slice Thickness :  100  μm
Tissue Shrinkage :  Not reported
Objective Type :  oil
Magnification :  100x
Reconstruction Method :  Imaris
Date of Deposition :  2024-05-24
Date of Upload :  2024-06-25
Persistence Vector :  16p11-THC-at-P72_mPFC.pvec
Note :  This reconstruction was obtained from a mouse treated daily with a single subcutaneous injection (s.c.) of vehicle during adulthood (P70-P72).

Reference Article
Related Article Reference :  Microglial cannabinoid receptor type 1 mediates social memory deficits in mice produced by adolescent THC exposure and 16p11.2 duplication.

Measurements
Soma Surface :  N/A
Number of Stems :  2
Number of Bifurcations :  24
Number of Branches :  50
Overall Width :  7.28 μm
Overall Height :  58.57 μm
Overall Depth :  58.26 μm
Average Diameter :  0.45 μm
Total Length :  419.85 μm
Total Surface :  601.99 μm2
Total Volume :  106.95 μm3
Max Euclidean Distance :  62.28 μm
Max Path Distance :  93.95 μm
Max Branch Order :  10
Average Contraction :  0.92
Total Fragmentation :  945
Partition Asymmetry :  0.37
Average Rall's Ratio :  2.01
Average Bifurcation Angle Local :  69.39°
Average Bifurcation Angle Remote :  82.1°
Fractal Dimension :  1.04

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